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BMCBI
2008
105views more  BMCBI 2008»
13 years 9 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
BMCBI
2007
148views more  BMCBI 2007»
13 years 9 months ago
Evaluation of gene-expression clustering via mutual information distance measure
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...
Ido Priness, Oded Maimon, Irad E. Ben-Gal
BMCBI
2007
113views more  BMCBI 2007»
13 years 9 months ago
miRAS: a data processing system for miRNA expression profiling study
Background: The study of microRNAs (miRNAs) is attracting great considerations. Recent studies revealed that miRNAs play as important regulators of gene expression and some even a...
Feng Tian, Huayue Zhang, Xinyu Zhang, Chi Song, Yo...
BMCBI
2011
13 years 13 days ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
TKDE
2008
152views more  TKDE 2008»
13 years 8 months ago
SRDA: An Efficient Algorithm for Large-Scale Discriminant Analysis
Linear Discriminant Analysis (LDA) has been a popular method for extracting features that preserves class separability. The projection functions of LDA are commonly obtained by max...
Deng Cai, Xiaofei He, Jiawei Han