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» An Efficient Method for Multiple Sequence Alignment
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BMCBI
2008
140views more  BMCBI 2008»
13 years 8 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2007
112views more  BMCBI 2007»
13 years 8 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
NAR
2010
140views more  NAR 2010»
13 years 2 months ago
GUIDANCE: a web server for assessing alignment confidence scores
Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE ...
Osnat Penn, Eyal Privman, Haim Ashkenazy, Giddy La...
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
IPPS
2006
IEEE
14 years 2 months ago
Multiple sequence alignment by quantum genetic algorithm
In this paper we describe a new approach for the well known problem in bioinformatics: Multiple Sequence Alignment (MSA). MSA is fundamental task as it represents an essential pla...
L. Abdesslem, M. Soham, B. Mohamed