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» An Evolutionary Approach for Molecular Docking
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BMCBI
2005
108views more  BMCBI 2005»
13 years 7 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
NAR
2011
159views Computer Vision» more  NAR 2011»
12 years 10 months ago
SuperSweet - a resource on natural and artificial sweetening agents
A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, D-amino acids and large proteins. Carbohydrates play a particularly big role in hu...
Jessica Ahmed, Saskia Preissner, Mathias Dunkel, C...
WOB
2004
134views Bioinformatics» more  WOB 2004»
13 years 9 months ago
Reconstruction of Phylogenetic Trees using the Ant Colony Optimization Paradigm
We developed a new approach for the reconstruction of phylogenetic trees using ant colony optimization metaheuristics.Atree is constructed using a fully connected graph and the pro...
Heitor S. Lopes, Mauricio Perretto
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
An ant colony optimisation algorithm for the 2D and 3D hydrophobic polar protein folding problem
Background: The protein folding problem is a fundamental problems in computational molecular biology and biochemical physics. Various optimisation methods have been applied to for...
Alena Shmygelska, Holger H. Hoos
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
14 years 29 days ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster