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BMCBI
2007
173views more  BMCBI 2007»
13 years 8 months ago
Predicting state transitions in the transcriptome and metabolome using a linear dynamical system model
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
Ryoko Morioka, Shigehiko Kanaya, Masami Y. Hirai, ...
BMCBI
2010
83views more  BMCBI 2010»
13 years 8 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
BMCBI
2007
109views more  BMCBI 2007»
13 years 8 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...
BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
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