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BMCBI
2007
87views more  BMCBI 2007»
13 years 7 months ago
A manually curated database of tetrapod mitochondrially encoded tRNA sequences and secondary structures
Background: Mitochondrial tRNAs have been the subject of study for structural biologists interested in their secondary structure characteristics, evolutionary biologists have rese...
Konstantin Yu Popadin, Leila A. Mamirova, Fyodor A...
BMCBI
2005
147views more  BMCBI 2005»
13 years 7 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen
BMCBI
2006
158views more  BMCBI 2006»
13 years 7 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
WABI
2004
Springer
14 years 22 days ago
Chaining Algorithms for Alignment of Draft Sequence
Abstract. In this paper we propose a chaining method that can align a draft genomic sequence against a finished genome. We introduce the use of an overlap tree to enhance the state...
Mukund Sundararajan, Michael Brudno, Kerrin Small,...
CSB
2003
IEEE
14 years 21 days ago
A New Approach for Gene Annotation Using Unambiguous Sequence Joining
The problem addressed by this paper is accurate and automatic gene annotation following precise identification/annotation of exon and intron boundaries of biologically verified ...
Alexandre Tchourbanov, Daniel Quest, Hesham H. Ali...