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BMCBI
2008
152views more  BMCBI 2008»
13 years 7 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
NAR
2011
216views Computer Vision» more  NAR 2011»
12 years 10 months ago
ChemProt: a disease chemical biology database
Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a criti...
Olivier Taboureau, Sonny Kim Nielsen, Karine Audou...
TVCG
2008
147views more  TVCG 2008»
13 years 7 months ago
Cerebral: Visualizing Multiple Experimental Conditions on a Graph with Biological Context
Systems biologists use interaction graphs to model the behavior of biological systems at the molecular level. In an iterative process, such biologists observe the reactions of livi...
Aaron Barsky, Tamara Munzner, Jennifer L. Gardy, R...
CEC
2007
IEEE
13 years 11 months ago
Evolving hypernetwork classifiers for microRNA expression profile analysis
Abstract-- High-throughput microarrays inform us on different outlooks of the molecular mechanisms underlying the function of cells and organisms. While computational analysis for ...
Sun Kim, Soo-Jin Kim, Byoung-Tak Zhang
CSB
2004
IEEE
173views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Gene Ontology Friendly Biclustering of Expression Profiles
The soundness of clustering in the analysis of gene expression profiles and gene function prediction is based on the hypothesis that genes with similar expression profiles may imp...
Jinze Liu, Wei Wang 0010, Jiong Yang