Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
Complex systems exhibit emergent patterns of behavior at different levels of organization. Powerful network analysis methods, developed in physics and social sciences, have been s...
Andre Nash, Christian Bird, Earl T. Barr, Premkuma...
In this paper, we propose a novel appearance-based representation, called Structured Ordinal Feature (SOF). SOF is a binary string encoded by combining eight ordinal blocks in a ci...
ShengCai Liao, Zhen Lei, Stan Z. Li, Xiaotong Yuan...
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...