24 search results - page 3 / 5 » Analysis of Large-Scale Sequencing of Small RNAs |
BMCBI
2004
13 years 7 months ago
2004
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
BMCBI
2010
13 years 7 months ago
2010
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
BMCBI
2006
13 years 7 months ago
2006
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
JCB
2000
13 years 7 months ago
2000
Large scale gene duplication is a major force driving the evolution of genetic functional innovation. Whole genome duplications are widely believed to have played an important rol...
BMCBI
2010
13 years 7 months ago
2010
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...