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» Analysis of Microarray Titration Experiments
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BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
poolMC: Smart pooling of mRNA samples in microarray experiments
Background: Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a microarray chip....
Raghunandan M. Kainkaryam, Angela Bruex, Anna C. G...
BMCBI
2004
106views more  BMCBI 2004»
13 years 7 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
JMLR
2010
136views more  JMLR 2010»
13 years 2 months ago
Evaluation Method for Feature Rankings and their Aggregations for Biomarker Discovery
In this paper we investigate the problem of evaluating ranked lists of biomarkers, which are typically an output of the analysis of high-throughput data. This can be a list of pro...
Ivica Slavkov, Bernard Zenko, Saso Dzeroski
BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis
Background: There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often sp...
Ari B. Kahn, Michael C. Ryan, Hongfang Liu, Barry ...
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
An algorithm for automatic evaluation of the spot quality in two-color DNA microarray experiments
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
Eugene Novikov, Emmanuel Barillot