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BMCBI
2007
96views more  BMCBI 2007»
13 years 7 months ago
Structure and function predictions of the Msa protein in Staphylococcus aureus
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
Vijayaraj Nagarajan, Mohamed O. Elasri
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
13 years 11 months ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2008
84views more  BMCBI 2008»
13 years 7 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2008
95views more  BMCBI 2008»
13 years 7 months ago
PURE: A webserver for the prediction of domains in unassigned regions in proteins
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
BMCBI
2006
106views more  BMCBI 2006»
13 years 7 months ago
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their...
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B....