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151
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BMCBI
2004
208views more  BMCBI 2004»
15 years 3 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
146
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BMCBI
2004
133views more  BMCBI 2004»
15 years 3 months ago
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
Robin D. Dowell, Sean R. Eddy
130
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BMCBI
2004
158views more  BMCBI 2004»
15 years 3 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...
124
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CPHYSICS
2004
87views more  CPHYSICS 2004»
15 years 3 months ago
Vlasov simulations on an adaptive phase-space grid
We introduce here a new method for the numerical resolution of the Vlasov equation on a phase space grid using an adaptive semi-Lagrangian method. The adaptivity is obtained throu...
Michael Gutnic, Matthieu Haefele, I. Paun, Eric So...
116
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JAIR
2000
123views more  JAIR 2000»
15 years 3 months ago
Backbone Fragility and the Local Search Cost Peak
The local search algorithm WSat is one of the most successful algorithms for solving the satisfiability (SAT) problem. It is notably effective at solving hard Random 3-SAT instanc...
Josh Singer, Ian P. Gent, Alan Smaill
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