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ALMOB
2006
155views more  ALMOB 2006»
13 years 8 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
GECCO
2005
Springer
180views Optimization» more  GECCO 2005»
14 years 2 months ago
Inference of gene regulatory networks using s-system and differential evolution
In this work we present an improved evolutionary method for inferring S-system model of genetic networks from the time series data of gene expression. We employed Differential Ev...
Nasimul Noman, Hitoshi Iba
NAR
2011
225views Computer Vision» more  NAR 2011»
12 years 11 months ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
BMCBI
2006
122views more  BMCBI 2006»
13 years 8 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2007
148views more  BMCBI 2007»
13 years 8 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole