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BMCBI
2007
175views more  BMCBI 2007»
13 years 8 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
BMCBI
2008
141views more  BMCBI 2008»
13 years 8 months ago
Functional discrimination of membrane proteins using machine learning techniques
Background: Discriminating membrane proteins based on their functions is an important task in genome annotation. In this work, we have analyzed the characteristic features of amin...
M. Michael Gromiha, Yukimitsu Yabuki
BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
Evaluation and comparison of mammalian subcellular localization prediction methods
Background: Determination of the subcellular location of a protein is essential to understanding its biochemical function. This information can provide insight into the function o...
Josefine Sprenger, J. Lynn Fink, Rohan D. Teasdale
GECCO
2006
Springer
172views Optimization» more  GECCO 2006»
13 years 11 months ago
Multi-objective optimisation of the protein-ligand docking problem in drug discovery
The pharmaceutical industry is facing an ever-increasing demand to discover novel drugs that are more effective and safer than existing ones. The industry faces huge problem in im...
A. Oduguwa, A. Tiwari, S. Fiorentino, R. Roy
SAC
2005
ACM
14 years 1 months ago
Comparing approaches to predict transmembrane domains in protein sequences
There are today several systems for predicting transmembrane domains in membrane protein sequences. As they are based on different classifiers as well as different pre- and post-p...
Paul Davidsson, Johan Hagelbäck, Kenny Svenss...