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BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
CGF
2008
151views more  CGF 2008»
13 years 7 months ago
Navigation and Exploration of Interconnected Pathways
Visualizing pathways, i. e. models of cellular functional networks, is a challenging task in computer assisted biomedicine. Pathways are represented as large collections of interw...
Marc Streit, Michael Kalkusch, Karl Kashofer, Diet...
ICASSP
2009
IEEE
14 years 2 months ago
Microarray classification using block diagonal linear discriminant analysis with embedded feature selection
In this paper, block diagonal linear discriminant analysis (BDLDA) is improved and applied to gene expression data. BDLDA is a classification tool with embedded feature selection...
Lingyan Sheng, Roger Pique-Regi, Shahab Asgharzade...
BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
FLAIRS
2003
13 years 9 months ago
Topic Extraction and Extension to Support Concept Mapping
Successful knowledge management may depend not only on knowledge capture, but on knowledge construction—on formulating new and useful knowledge that was not previously available...
David B. Leake, Ana Gabriela Maguitman, Thomas Rei...