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142
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BMCBI
2008
15 years 2 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
137
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BMCBI
2007
15 years 2 months ago
2007
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
127
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BMCBI
2010
15 years 2 months ago
2010
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
144
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BMCBI
2007
15 years 2 months ago
2007
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
108
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CERA
2010
15 years 2 months ago
2010
Multilevel design problems are typically decomposed into a hierarchy of distributed and strongly coupled sub-problems, each solved by design teams with specialized knowledge and t...