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126
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
134
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
128
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
153
Voted
BMCBI
2008
15 years 3 months ago
2008
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
124
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in d...