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» Assessment of protein set coherence using functional annotat...
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BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
NAR
2011
223views Computer Vision» more  NAR 2011»
12 years 10 months ago
HitPredict: a database of quality assessed protein-protein interactions in nine species
Despite the availability of a large number of protein– protein interactions (PPIs) in several species, researchers are often limited to using very small subsets in a few organis...
Ashwini Patil, Kenta Nakai, Haruki Nakamura
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
BMCBI
2007
131views more  BMCBI 2007»
13 years 7 months ago
An improved method for identifying functionally linked proteins using phylogenetic profiles
Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
BMCBI
2006
195views more  BMCBI 2006»
13 years 7 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona