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ICAI
2007
13 years 9 months ago
Mining and Dynamic Simulation of Sub-Networks from Large Biomolecular Networks
Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As biomolecular...
Xiaohua Hu, Fang-Xiang Wu, Michael K. Ng, Bahrad A...
JCP
2008
121views more  JCP 2008»
13 years 7 months ago
Towards Design Space Exploration for Biological Systems
For both embedded systems and biological cell systems, design is a feature that defines their identity. The assembly of different components in designs of both systems can vary wid...
Simon Polstra, Tessa E. Pronk, Andy D. Pimentel, T...
BMCBI
2005
77views more  BMCBI 2005»
13 years 7 months ago
Ontological visualization of protein-protein interactions
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
Harold J. Drabkin, Christopher Hollenbeck, David P...
BMCBI
2007
124views more  BMCBI 2007»
13 years 7 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
BMCBI
2010
183views more  BMCBI 2010»
13 years 5 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...