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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
BMCBI
2007
134views more  BMCBI 2007»
13 years 7 months ago
PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results
Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating...
Ji He, Xinbin Dai, Xuechun Zhao
BMCBI
2007
134views more  BMCBI 2007»
13 years 7 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...