Background: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative g...
Debra L. Fulton, Yvonne Y. Li, Matthew R. Laird, B...
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
The explosive growth in genomic (and soon, expression and proteomic) data, exemplified by the Human Genome Project, is a fertile domain for the application of multi-agent informat...
Keith Decker, Salim Khan, Carl Schmidt, Dennis Mic...
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
Sung Tae Doh, Yunyu Zhang, Matthew H. Temple, Li C...
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...