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BMCBI
2010
13 years 7 months ago
2010
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...
BMCBI
2008
13 years 7 months ago
2008
Background: High-throughput screening of pharmaceutical compound activity in tissue culture experiments requires time-consuming repeated analysis of the large amounts of data gene...
BMCBI
2008
13 years 7 months ago
2008
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
BMCBI
2007
13 years 7 months ago
2007
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
BMCBI
2007
13 years 7 months ago
2007
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...