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BMCBI
2010
86views more  BMCBI 2010»
13 years 7 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...
BMCBI
2007
145views more  BMCBI 2007»
13 years 7 months ago
Colony size measurement of the yeast gene deletion strains for functional genomics
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...
Negar Memarian, Matthew Jessulat, Javad Alirezaie,...
BMCBI
2007
109views more  BMCBI 2007»
13 years 7 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2008
163views more  BMCBI 2008»
13 years 7 months ago
Nuclear staining and relative distance for quantifying epidermal differentiation in biomarker expression profiling
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
Thora Pommerencke, Thorsten Steinberg, Hartmut Dic...