Background: The current progress in sequencing projects calls for rapid, reliable and accurate function assignments of gene products. A variety of methods has been designed to ann...
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
Robert F. Murphy, Michael V. Boland, Meel Velliste
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
To better understand the development and function of the mammalian brain, researchers have begun to systematically collect a large number of gene expression patterns throughout the...
Ioannis A. Kakadiaris, Musodiq Bello, Shiva Arunac...
Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subc...