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121
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BMCBI
2005
109views more  BMCBI 2005»
15 years 3 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
135
Voted
BMCBI
2005
77views more  BMCBI 2005»
15 years 3 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
130
Voted
BMCBI
2005
111views more  BMCBI 2005»
15 years 3 months ago
Improving interoperability between microbial information and sequence databases
Background: Biological resources are essential tools for biomedical research. Their availability is promoted through on-line catalogues. Common Access to Biological Resources and ...
Paolo Romano, Peter Dawyndt, Francesca Piersigilli...
142
Voted
BMCBI
2004
90views more  BMCBI 2004»
15 years 3 months ago
Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
Igor Dozmorov, Nicholas Knowlton, Yuhong Tang, Mic...
143
Voted
BMCBI
2004
119views more  BMCBI 2004»
15 years 3 months ago
Genome SEGE: A database for 'intronless' genes in eukaryotic genomes
Background: A number of completely sequenced eukaryotic genome data are available in the public domain. Eukaryotic genes are either 'intron containing' or 'intronle...
Meena K. Sakharkar, Pandjassarame Kangueane