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BMCBI
2010
227views more  BMCBI 2010»
13 years 11 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2007
97views more  BMCBI 2007»
13 years 11 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
BMCBI
2007
182views more  BMCBI 2007»
13 years 11 months ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...
BMCBI
2008
129views more  BMCBI 2008»
13 years 11 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
WIAS
2008
128views more  WIAS 2008»
13 years 10 months ago
Considering operational issues for multiagent conceptual inferencing in a distributed information retrieval application
Our system, based on a multiagent framework called collaborative understanding of distributed knowledge (CUDK), is designed with the overall goal of balancing agents' conceptu...
Leen-Kiat Soh