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GECCO
2005
Springer
136views Optimization» more  GECCO 2005»
14 years 1 months ago
Evolutionary computation and the c-value paradox
The C-value Paradox is the name given in biology to the wide variance in and often very large amount of DNA in eukaryotic genomes and the poor correlation between DNA length and p...
Sean Luke
WABI
2001
Springer
134views Bioinformatics» more  WABI 2001»
14 years 4 days ago
Comparing Assemblies Using Fragments and Mate-Pairs
Using current technology, large consecutive stretches of DNA (such as whole chromosomes) are usually assembled from short fragments obtained by shotgun sequencing, or from fragment...
Daniel H. Huson, Aaron L. Halpern, Zhongwu Lai, Eu...
SODA
2001
ACM
87views Algorithms» more  SODA 2001»
13 years 9 months ago
Gossip is synteny: incomplete gossip and an exact algorithm for syntenic distance
The syntenic distance between two genomes is given by the minimum number of fusions, fissions, and translocations required to transform one into the other, ignoring the order of g...
David Liben-Nowell
BMCBI
2008
105views more  BMCBI 2008»
13 years 7 months ago
Objective and automated protocols for the evaluation of biomedical search engines using No Title Evaluation protocols
Background: The evaluation of information retrieval techniques has traditionally relied on human judges to determine which documents are relevant to a query and which are not. Thi...
Fabien Campagne
BMCBI
2007
92views more  BMCBI 2007»
13 years 7 months ago
Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription fa
Background: Synthetic transcription factors (STFs) promise to offer a powerful new therapeutic against Cancer, AIDS, and genetic disease. Currently, 10% of drugs are of this type,...
Stephen Winters-Hilt, Amanda Davis, Iftekhar Amin,...