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» Bayesian modelling of shared gene function
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JMLR
2011
167views more  JMLR 2011»
13 years 4 months ago
Logistic Stick-Breaking Process
A logistic stick-breaking process (LSBP) is proposed for non-parametric clustering of general spatially- or temporally-dependent data, imposing the belief that proximate data are ...
Lu Ren, Lan Du, Lawrence Carin, David B. Dunson
NAR
2011
225views Computer Vision» more  NAR 2011»
13 years 19 days ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
BMCBI
2008
160views more  BMCBI 2008»
13 years 10 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
BMCBI
2004
146views more  BMCBI 2004»
13 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2008
148views more  BMCBI 2008»
13 years 10 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan