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» Biclustering of Expression Data Using Simulated Annealing
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BMCBI
2010
125views more  BMCBI 2010»
13 years 3 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...
BMCBI
2007
215views more  BMCBI 2007»
13 years 8 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
BMCBI
2010
143views more  BMCBI 2010»
13 years 8 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
BMCBI
2007
104views more  BMCBI 2007»
13 years 8 months ago
Comparative evaluation of gene-set analysis methods
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
BMCBI
2010
132views more  BMCBI 2010»
13 years 8 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter