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BMCBI
2004
111views more  BMCBI 2004»
13 years 9 months ago
Multiclass discovery in array data
Background: A routine goal in the analysis of microarray data is to identify genes with expression levels that correlate with known classes of experiments. In a growing number of ...
Yingchun Liu, Markus Ringnér
BMCBI
2004
151views more  BMCBI 2004»
13 years 9 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
COMPLEXITY
2004
165views more  COMPLEXITY 2004»
13 years 9 months ago
Sex promotes gamete selection: A quantitative comparative study of features favoring the evolution of sex
: Explaining the maintenance of sexual reproduction remains one of the greatest challenges in biology. The theoretical oddity of sex is based on at least three advantages that asex...
Klaus Jaffe
BMCBI
2002
120views more  BMCBI 2002»
13 years 9 months ago
tacg - a grep for DNA
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...
Harry Mangalam
BMCBI
2002
126views more  BMCBI 2002»
13 years 9 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy