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BMCBI
2007
126views more  BMCBI 2007»
15 years 4 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
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BMCBI
2007
147views more  BMCBI 2007»
15 years 4 months ago
Comparative analysis of long DNA sequences by per element information content using different contexts
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
Trevor I. Dix, David R. Powell, Lloyd Allison, Jul...
CORR
2007
Springer
100views Education» more  CORR 2007»
15 years 4 months ago
Identifying statistical dependence in genomic sequences via mutual information estimates
Questions of understanding and quantifying the representation and amount of information in organisms have become a central part of biological research, as they potentially hold th...
H. M. Aktulga, I. Kontoyiannis, L. A. Lyznik, Luka...
NAR
2008
191views more  NAR 2008»
15 years 4 months ago
The BioGRID Interaction Database: 2008 update
The Biological General Repository for Interaction Datasets (BioGRID) database (http://www. thebiogrid.org) was developed to house and distribute collections of protein and genetic...
Bobby-Joe Breitkreutz, Chris Stark, Teresa Reguly,...
GPEM
2007
87views more  GPEM 2007»
15 years 4 months ago
Motility, mixing, and multicellularity
Abstract. A fundamental issue in evolutionary biology is the transition from unicellular to multicellular organisms, and the cellular differentiation that accompanies the increase...
Cristian A. Solari, John O. Kessler, Raymond E. Go...