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» Biological networks in metabolic P systems
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BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Machine learning methods for metabolic pathway prediction
Background: A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is ...
Joseph M. Dale, Liviu Popescu, Peter D. Karp
ICDM
2006
IEEE
152views Data Mining» more  ICDM 2006»
14 years 1 months ago
Application of Graph-based Data Mining to Metabolic Pathways
We present a method for finding biologically meaningful patterns on metabolic pathways using the SUBDUE graph-based relational learning system. A huge amount of biological data t...
Chang Hun You, Lawrence B. Holder, Diane J. Cook
BMCBI
2010
125views more  BMCBI 2010»
13 years 7 months ago
Compartmentalization of the Edinburgh Human Metabolic Network
Background: Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in d...
Tong Hao, Hongwu Ma, Xue-Ming Zhao, Igor Goryanin
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...
IDA
2009
Springer
13 years 4 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis