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BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
HPCA
2008
IEEE
14 years 8 months ago
Performance-aware speculation control using wrong path usefulness prediction
Fetch gating mechanisms have been proposed to gate the processor pipeline to reduce the wasted energy consumption due to wrongpath (i.e. mis-speculated) instructions. These scheme...
Chang Joo Lee, Hyesoon Kim, Onur Mutlu, Yale N. Pa...
SAMOS
2007
Springer
14 years 1 months ago
Online Prediction of Applications Cache Utility
— General purpose architectures are designed to offer average high performance regardless of the particular application that is being run. Performance and power inefficiencies a...
Miquel Moretó, Francisco J. Cazorla, Alex R...
BMCBI
2007
96views more  BMCBI 2007»
13 years 7 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
BMCBI
2010
145views more  BMCBI 2010»
13 years 2 months ago
Directionality in protein fold prediction
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
Jonathan J. Ellis, Fabien P. E. Huard, Charlotte M...