Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
Despite recent progress in high-throughput experimental studies, systems level visualization and analysis of large protein interaction networks (ppi) remains a challenging task, g...
Boon-Siew Seah, Sourav S. Bhowmick, Charles Forbes...
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...