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» Can we Find Molecular Signatures from Gene Expression Data
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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 2 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
14 years 23 days ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
BMCBI
2007
113views more  BMCBI 2007»
13 years 9 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
ISCAPDCS
2007
13 years 10 months ago
Architectural requirements of parallel computational biology applications with explicit instruction level parallelism
—The tremendous growth in the information culture, efficient digital searches are needed to extract and identify information from huge data. The notion that evolution in silicon ...
Naeem Zafar Azeemi
BMCBI
2008
162views more  BMCBI 2008»
13 years 9 months ago
Background correction using dinucleotide affinities improves the performance of GCRMA
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas