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» Case Study of a Functional Genomics Application
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BMCBI
2008
112views more  BMCBI 2008»
13 years 7 months ago
A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regul
Background: Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Al...
Arnab Bhattacharya, Sasha Levy, Adria LeBoeuf, Mic...
BMCBI
2005
246views more  BMCBI 2005»
13 years 7 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...
RECOMB
2006
Springer
14 years 8 months ago
Integrated Protein Interaction Networks for 11 Microbes
We have combined four different types of functional genomic data to create high coverage protein interaction networks for 11 microbes. Our integration algorithm naturally handles s...
Balaji S. Srinivasan, Antal F. Novak, Jason Flanni...
BMCBI
2010
150views more  BMCBI 2010»
13 years 7 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
BMCBI
2010
89views more  BMCBI 2010»
13 years 7 months ago
Detection of gene pathways with predictive power for breast cancer prognosis
Background: Prognosis is of critical interest in breast cancer research. Biomedical studies suggest that genomic measurements may have independent predictive power for prognosis. ...
Shuangge Ma, Michael R. Kosorok