Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
Nathan Salomonis, Kristina Hanspers, Alexander C. ...
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
Mattia Pelizzola, Norman Pavelka, Maria Foti, Paol...
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...