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BICOB
2010
Springer
13 years 7 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
CINQ
2004
Springer
116views Database» more  CINQ 2004»
13 years 10 months ago
Contribution to Gene Expression Data Analysis by Means of Set Pattern Mining
Abstract. One of the exciting scientific challenges in functional genomics concerns the discovery of biologically relevant patterns from gene expression data. For instance, it is e...
Ruggero G. Pensa, Jérémy Besson, C&e...
BMCBI
2005
102views more  BMCBI 2005»
13 years 6 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
BMCBI
2010
154views more  BMCBI 2010»
13 years 6 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
APBC
2004
138views Bioinformatics» more  APBC 2004»
13 years 8 months ago
Whole-Genome Functional Classification of Genes by Latent Semantic Analysis on Microarray Data
Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments. The resulti...
See-Kiong Ng, Zexuan Zhu, Yew-Soon Ong