524 search results - page 18 / 105 » Challenges of sequencing human genomes |
BMCBI
2010
13 years 9 months ago
2010
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
RECOMB
2009
Springer
14 years 3 months ago
2009
Springer
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
BMCBI
2006
13 years 9 months ago
2006
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
BMCBI
2010
13 years 9 months ago
2010
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
NAR
2011
12 years 11 months ago
2011
High-throughput genomic technologies have been used to explore personal human genomes for the past few years. Although the integration of technologies is important for high-accura...