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» Challenges of sequencing human genomes
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AC
2004
Springer
13 years 8 months ago
Shotgun Sequence Assembly
Shotgun sequencing is the most widely used technique for determining the DNA sequence of organisms. It involves breaking up the DNA into many small pieces that can be read by auto...
Mihai Pop
VISUALIZATION
1995
IEEE
14 years 11 days ago
Visualization of Biological Sequence Similarity Search Results
Biological sequence similarity analysis presents visualization challenges, primarily because of the massive amounts of discrete, multi-dimensional data. Genomic data generated by ...
Ed Huai-hsin Chi, Phillip Barry, Elizabeth Shoop, ...
IQ
2003
13 years 10 months ago
Data Quality in Genome Databases
: Genome databases store data about molecular biological entities such as genes, proteins, diseases, etc. The main purpose of creating and maintaining such databases in commercial ...
Heiko Müller, Felix Naumann
RECOMB
2005
Springer
14 years 9 months ago
Using Multiple Alignments to Improve Gene Prediction
The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structur...
Samuel S. Gross, Michael R. Brent
RECOMB
2009
Springer
14 years 9 months ago
Storage and Retrieval of Individual Genomes
A repetitive sequence collection is one where portions of a base sequence of length n are repeated many times with small variations, forming a collection of total length N. Example...
Gonzalo Navarro, Jouni Sirén, Niko Väl...