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» Challenges of sequencing human genomes
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BMCBI
2007
265views more  BMCBI 2007»
13 years 9 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
RECOMB
2003
Springer
14 years 9 months ago
Transforming men into mice: the Nadeau-Taylor chromosomal breakage model revisited
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Pavel A. Pevzner, Glenn Tesler
PREMI
2005
Springer
14 years 2 months ago
Computational Molecular Biology of Genome Expression and Regulation
Abstract. Technological advances in experimental and computational molecular biology have revolutionized the whole fields of biology and medicine. Large-scale sequencing, expressio...
Michael Q. Zhang
NAR
2011
208views Computer Vision» more  NAR 2011»
12 years 11 months ago
The UCSC Genome Browser database: update 2011
The University of California, Santa Cruz Genome Browser (http://genome.ucsc.edu) offers online access to a database of genomic sequence and annotation data for a wide variety of o...
Pauline A. Fujita, Brooke L. Rhead, Ann S. Zweig, ...
ICDT
2003
ACM
150views Database» more  ICDT 2003»
14 years 2 months ago
Bioinformatics Adventures in Database Research
Informatics has helped launch molecular biology into the genomic era. It appears certain that informatics will remain a major contributor to molecular biology in the post-genome er...
Jinyan Li, See-Kiong Ng, Limsoon Wong