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» Challenges of sequencing human genomes
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BIBM
2008
IEEE
110views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Genome Alignments Using MPI-LAGAN
We develop a parallel algorithm for a widely used whole genome alignment method called LAGAN. We use the MPI-based protocol to develop parallel solutions for two phases of the alg...
Ruinan Zhang, Huzefa Rangwala, George Karypis
TPDS
1998
112views more  TPDS 1998»
13 years 8 months ago
Parallel Computation in Biological Sequence Analysis
—A massive volume of biological sequence data is available in over 36 different databases worldwide, including the sequence data generated by the Human Genome project. These data...
Tieng K. Yap, Ophir Frieder, Robert L. Martino
BMCBI
2006
141views more  BMCBI 2006»
13 years 9 months ago
Asymptotic behaviour and optimal word size for exact and approximate word matches between random sequences
Background: The number of k-words shared between two sequences is a simple and effcient alignment-free sequence comparison method. This statistic, D2, has been used for the cluste...
Sylvain Forêt, Miriam R. Kantorovitz, Conrad...
BMCBI
2007
129views more  BMCBI 2007»
13 years 9 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
NAR
2010
202views more  NAR 2010»
13 years 3 months ago
dbDEPC: a database of Differentially Expressed Proteins in human Cancers
Cancer-related investigations have long been in the limelight of biomedical research. Years of effort from scientists and doctors worldwide have generated large amounts of data at...
Hong Li, Ying He, Guohui Ding, Chuan Wang, Lu Xie,...