524 search results - page 45 / 105 » Challenges of sequencing human genomes |
BMCBI
2011
13 years 15 days ago
2011
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
BMCBI
2010
13 years 9 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
BMCBI
2007
13 years 9 months ago
2007
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
NAR
2011
2011
NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data
12 years 11 months ago
Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...
BMCBI
2010
13 years 9 months ago
2010
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...