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» Challenges of sequencing human genomes
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BMCBI
2010
214views more  BMCBI 2010»
13 years 7 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
161views more  BMCBI 2010»
13 years 5 months ago
Application of Wavelet Packet Transform to detect genetic polymorphisms by the analysis of inter-Alu PCR patterns
Background: The analysis of Inter-Alu PCR patterns obtained from human genomic DNA samples is a promising technique for a simultaneous analysis of many genomic loci flanked by Alu...
Maurizio Cardelli, Matteo Nicoli, Armando Bazzani,...
SPIRE
2005
Springer
14 years 1 months ago
Composite Pattern Discovery for PCR Application
We consider the problem of finding pairs of short patterns such that, in a given input sequence of length n, the distance between each pair’s patterns is at least α. The proble...
Stanislav Angelov, Shunsuke Inenaga
BMCBI
2007
120views more  BMCBI 2007»
13 years 7 months ago
Recognition of interferon-inducible sites, promoters, and enhancers
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...
Elena A. Ananko, Yury V. Kondrakhin, Tatyana I. Me...
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
VariVis: a visualisation toolkit for variation databases
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
Timothy D. Smith, Richard G. H. Cotton