Protein-protein interactions are critical to many biological processes, extending from the formation of cellular macromolecular structures and enzymatic complexes to the regulation...
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Background: Gene expression databases are key resources for microarray data management and analysis and the importance of a proper annotation of their content is well understood. ...
Andrea Splendiani, Marco Brandizi, Gael Even, Otta...
Background: Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite ...
Many applications require a computer representation of 2D shape, usually described by a set of 2D points. The challenge of this representation is that it must not only capture the...