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BMCBI
2007
131views more  BMCBI 2007»
13 years 10 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
BMCBI
2008
95views more  BMCBI 2008»
13 years 10 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2008
103views more  BMCBI 2008»
13 years 10 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
BMCBI
2008
102views more  BMCBI 2008»
13 years 10 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
CN
2008
98views more  CN 2008»
13 years 10 months ago
Description and simulation of dynamic mobility networks
During the last decade, the study of large scale complex networks has attracted a substantial amount of attention and works from several domains: sociology, biology, computer scie...
Antoine Scherrer, Pierre Borgnat, Eric Fleury, Jea...