Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Abstract. The purpose of this work is to demonstrate that it is possible to cluster contact maps for pairs of alpha helices such that each of the clusters corresponds to a group of...
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...