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BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...
BMCBI
2010
112views more  BMCBI 2010»
13 years 7 months ago
Knowledge-based analysis of microarrays for the discovery of transcriptional regulation relationships
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
14 years 28 days ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
ICMLA
2008
13 years 9 months ago
Ensemble Machine Methods for DNA Binding
We introduce three ensemble machine learning methods for analysis of biological DNA binding by transcription factors (TFs). The goal is to identify both TF target genes and their ...
Yue Fan, Mark A. Kon, Charles DeLisi