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» Comparative Genome Annotation for Mapping, Prediction and Di...
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BMCBI
2010
155views more  BMCBI 2010»
13 years 5 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2007
129views more  BMCBI 2007»
13 years 7 months ago
HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Hongya Zhao, Hong Yan
BMCBI
2004
148views more  BMCBI 2004»
13 years 7 months ago
Bioinformatics analysis of SARS coronavirus genome polymorphism
Background: We have compared 38 isolates of the SARS-CoV complete genome. The main goal was twofold: first, to analyze and compare nucleotide sequences and to identify positions o...
Gordana Pavlovic-Lazetic, Nenad S. Mitic, Milos V....
BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal