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» Comparing Sequences with Segment Rearrangements
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BMCBI
2007
154views more  BMCBI 2007»
13 years 7 months ago
Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms
Background: Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between genomes in ter...
Amit U. Sinha, Jaroslaw Meller
BMCBI
2011
12 years 11 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
BMCBI
2008
125views more  BMCBI 2008»
13 years 7 months ago
A fast algorithm for the multiple genome rearrangement problem with weighted reversals and transpositions
Background: Due to recent progress in genome sequencing, more and more data for phylogenetic reconstruction based on rearrangement distances between genomes become available. Howe...
Martin Bader, Mohamed Ibrahim Abouelhoda, Enno Ohl...
SAC
2002
ACM
13 years 7 months ago
Short inversions and conserved gene clusters
Two independent sets of recent observations on newly sequenced microbial genomes pertain to the prevalence of short inversion as a gene order rearrangement process and to the lack...
David Sankoff
BMCBI
2008
156views more  BMCBI 2008»
13 years 7 months ago
Chromhome: A rich internet application for accessing comparative chromosome homology maps
Background: Comparative genomics has become a significant research area in recent years, following the availability of a number of sequenced genomes. The comparison of genomes is ...
Sridevi Nagarajan, Willem Rens, James Stalker, Ton...