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» Comparing notions of randomness
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BMCBI
2007
83views more  BMCBI 2007»
13 years 8 months ago
Identification of sequence motifs significantly associated with antisense activity
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Kyle A. McQuisten, Andrew S. Peek
BMCBI
2008
201views more  BMCBI 2008»
13 years 8 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
Effects of dependence in high-dimensional multiple testing problems
Background: We consider effects of dependence among variables of high-dimensional data in multiple hypothesis testing problems, in particular the False Discovery Rate (FDR) contro...
Kyung In Kim, Mark A. van de Wiel
BMCBI
2008
139views more  BMCBI 2008»
13 years 8 months ago
Abbreviation definition identification based on automatic precision estimates
Background: The rapid growth of biomedical literature presents challenges for automatic text processing, and one of the challenges is abbreviation identification. The presence of ...
Sunghwan Sohn, Donald C. Comeau, Won Kim, W. John ...
BMCBI
2008
171views more  BMCBI 2008»
13 years 8 months ago
A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more
Background: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables ...
Harri T. Kiiveri